International Science Index


10007738

Electrode Engineering for On-Chip Liquid Driving by Using Electrokinetic Effect

Abstract:

High lamination in microchannel is one of the main challenges in on-chip components like micro total analyzer systems and lab-on-a-chips. Electro-osmotic force is highly effective in chip-scale. This research proposes a microfluidic-based micropump for low ionic strength solutions. Narrow microchannels are designed to generate an efficient electroosmotic flow near the walls. Microelectrodes are embedded in the lateral sides and actuated by low electric potential to generate pumping effect inside the channel. Based on the simulation study, the fluid velocity increases by increasing the electric potential amplitude. We achieve a net flow velocity of 100 µm/s, by applying +/- 2 V to the electrode structures. Our proposed low voltage design is of interest in conventional lab-on-a-chip applications.

References:
[1] R. H. Vafaie, M. Mehdipoor, A. Pourmand, E. Poorreza, and H. B. Ghavifekr, (2013) An electroosmotically-driven micromixer modified for high miniaturized microchannels using surface micromachining. Biotechnology and Bioprocess Engineering, vol. 18, pp. 594-605.
[2] H. A. Stone, A. D. Stroock, and A. Ajdari, "Engineering flows in small devices," Annu. Rev. Fluid Mech., vol. 36, 2004, pp. 381-411.
[3] T. M. Squires and S. R. Quake, "Microfluidics: Fluid physics at the nanoliter scale," Reviews of modern physics, vol. 77, 2005, p. 977.
[4] J. Atencia and D. J. Beebe, "Controlled microfluidic interfaces," Nature, vol. 437, 2004, pp. 648-655.
[5] J. Johari, et al., "Piezoelectric Micropump with Nanoliter Per Minute Flow for Drug Delivery Systems," Sains Malaysiana, vol. 40, pp. 275-281, 2011.
[6] M. McDonald, "High-Precision Jetting and Dispensing Applications Using A Piezoelectric Micropump," 2003, pp. 555-558.
[7] Jiang, L., Mikkelsen, J., Koo, J. M., Huber, D., Yao, S., Zhang, & Goodson, K. E. (2002). Closed-loop electroosmotic microchannel cooling system for VLSI circuits. Components and Packaging Technologies, IEEE Transactions on, 25(3), 347-355.
[8] H. Morgan and N. G. Green, AC electrokinetics: colloids and nanoparticles: Research Studies Press, 2003.
[9] B. J. Kirby and E. F. Hasselbrink Jr, "Zeta potential of microfluidic substrates: 1. Theory, experimental techniques, and effects on separations," Electrophoresis, vol. 25, pp. 187-202, 2004.
[10] A. Ajdari, "Pumping liquids using asymmetric electrode arrays," Physical Review E, vol. 61, pp. 45-48, 2000.
[11] A. Brown, et al., "Pumping of water with ac electric fields applied to asymmetric pairs of microelectrodes," Physical Review E, vol. 63, p. 016305, 2000.
[12] B. P. Cahill, et al., "Electro-osmotic pumping on application of phase-shifted signals to interdigitated electrodes," Sensors and Actuators B: Chemical, vol. 110, pp. 157-163, 2005.
[13] Pablo García Sánchez, "Travelling wave elctrokinetic micropumps," phd, University of Seville, 2004-2008.
[14] J. P. Urbanski, et al., "The effect of step height on the performance of three-dimensional ac electro-osmotic microfluidic pumps," Journal of colloid and interface science, vol. 309, pp. 332-341, 2007.
[15] P. Garcia-Sanchez and A. Ramos, "The effect of electrode height on the performance of travelling-wave electroosmotic micropumps," Microfluidics and nanofluidics, vol. 5, pp. 307-312, 2008.
[16] R. H. Vafaie, M. Mehdipoor, H. Mirzajani, H. B. Gavifekr, (2013) Numerical Simulation of Mixing Process in Tortuous Microchannel, Sensors & Transducers, vol. 151, pp. 30-35.
[17] Vafaie R H, Ghavifekr H B, Lintel H V, et al. (2016) Bi‐directional AC electrothermal micropump for on‐chip biological applications. Electrophoresis, 37 (5-6): 719-726.
[18] R. H. Vafaie, M. Mehdipoor, A. Pourmand, E. Poorreza, H. Badri “A Modified Electroosmotic Micromixer for Highly Miniaturized Microchannels”. Proceedings of the 8th International Symposium on Mechatronics and its Applications (ISMA12). April 10-12, Sharjah, UAE.
[19] Vafaie R. H, Ghavifekr H B. (2017) Configurable ACET micro-manipulator for high conductive mediums by using a novel electrode engineering. Microsys Technol, 23 (5): 1393-1403.
[20] Vafaie RH, Mehdipour M, Pourmand A, Ghavifekr HB. A novel miniaturized electroosmotically-driven micromixer modified by surface channel technology. InElectrical Engineering (ICEE), 2012 20th Iranian Conference on 2012 May 15 (pp. 124-129). IEEE.
[21] M. Mehdipour, R. H. Vafaie, A. Pourmand, E. Poorreza and H. B. Ghavifekr, (2012) A novel four phase AC electroosmotic micropump for lab-on-a-chip applications, Proceedings of the 8th International Symposium on Mechatronics and its Applications (ISMA12), April 10-12, Sharjah, UAE.
[22] Poorreza A, Vafaie R H, Mehdipoor M, et al. (2013) A microseparator based-on 4-phase travelling wave dielectrophoresis for Lab-on-a-chip applications. Indian J Pure Appl Phys, 51: 506-515.
[23] R. J. Hunter, L. R. White, and D. Y. C. Chan, Foundations of colloid science vol. 1: Clarendon press Oxford, 1987.
[24] E. Biddiss, D. Erickson, and D. Li, (2004) Heterogeneous surface charge enhanced micromixing for electrokinetic flows, Analytical chemistry, vol. 76, pp. 3208-3213.
[25] A. Ramos, et al., "AC electrokinetic pumping of liquids using arrays of microelectrodes," 2005, p. 305.
[26] Q. Yuan, K., Yang, J. Wu, (2014) Optimization of planar interdigitated microelectrode array for biofluid transport by AC electrothermal effect. Microfluidics and Nanofluidics, vol. 16, pp. 167-178.
[27] Ghandchi M, Vafaie RH. AC electrothermal actuation mechanism for on-chip mixing of high ionic strength fluids. Microsystem Technologies. 2016:1-3.